Identifying gaps in the locoregional management of early breast cancer: highlights from the Kyoto Consensus Conference.
Identifieur interne : 004E34 ( Main/Exploration ); précédent : 004E33; suivant : 004E35Identifying gaps in the locoregional management of early breast cancer: highlights from the Kyoto Consensus Conference.
Auteurs : Masakazu Toi [Japon] ; Eric P. Winer ; Takashi Inamoto ; John R. Benson ; John F. Forbes ; Michihide Mitsumori ; John F R. Robertson ; Hironobu Sasano ; Gunter Von Minckwitz ; Akira Yamauchi ; V Suzanne KlimbergSource :
- Annals of surgical oncology [ 1534-4681 ] ; 2011.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Tumeurs du sein.
- Congrès comme sujet, Femelle, Humains, Pronostic, Tumeurs du sein.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Breast Neoplasms.
- therapy : Breast Neoplasms.
- Congresses as Topic, Female, Humans, Prognosis.
Abstract
A consensus conference was held to investigate issues related to the local management of early breast cancer. Here, we highlight the major topics discussed at the conference and propose ideas for future studies. Regarding axillary management, we examined three major issues. First, we discussed whether the use of axillary reverse mapping could clarify the lymphatic system of breast and whether the ipsilateral arm might help avoid lymphedema. Second, the use of an indocyanine green fluorescent navigation system was discussed for intraoperative lymphatic mapping. These new issues should be examined further in practice. Finally, some agreement was reached on the importance of "four-node diagnosis" to aid in the diagnostic accuracy of sentinel nodes. Regarding breast treatment, there was general agreement that the clinical value of surgical margins in predicting local failure was dependent on the tumor's intrinsic biology and subtypes. For patients treated with preoperative chemotherapy, less extensive excision may be feasible in those who respond to systemic therapy in an acceptable manner. Most trials of preoperative chemotherapy lack outcome data on local recurrence. Therefore, there is a need for such data for overview analysis. We also agreed that radiation after mastectomy may be beneficial in node-positive cases where more than four nodes are involved. Throughout the discussions for both invasive and noninvasive disease, the investigation of nomograms was justified for major issues in the decision-making process, such as the presence or absence of microinvasion and the involvement of nonsentinel nodes in sentinel node-positive patients.
DOI: 10.1245/s10434-011-1666-7
PubMed: 21431404
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002697
- to stream PubMed, to step Curation: 002697
- to stream PubMed, to step Checkpoint: 002697
- to stream Ncbi, to step Merge: 004223
- to stream Ncbi, to step Curation: 004223
- to stream Ncbi, to step Checkpoint: 004223
- to stream Main, to step Merge: 004E70
- to stream Main, to step Curation: 004E34
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Identifying gaps in the locoregional management of early breast cancer: highlights from the Kyoto Consensus Conference.</title>
<author><name sortKey="Toi, Masakazu" sort="Toi, Masakazu" uniqKey="Toi M" first="Masakazu" last="Toi">Masakazu Toi</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, Japan. toi@kuhp.kyoto-u.ac.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto</wicri:regionArea>
<orgName type="university">Université de Kyoto</orgName>
<placeName><settlement type="city">Kyoto</settlement>
<region type="prefecture">Région du Kansai</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Winer, Eric P" sort="Winer, Eric P" uniqKey="Winer E" first="Eric P" last="Winer">Eric P. Winer</name>
</author>
<author><name sortKey="Inamoto, Takashi" sort="Inamoto, Takashi" uniqKey="Inamoto T" first="Takashi" last="Inamoto">Takashi Inamoto</name>
</author>
<author><name sortKey="Benson, John R" sort="Benson, John R" uniqKey="Benson J" first="John R" last="Benson">John R. Benson</name>
</author>
<author><name sortKey="Forbes, John F" sort="Forbes, John F" uniqKey="Forbes J" first="John F" last="Forbes">John F. Forbes</name>
</author>
<author><name sortKey="Mitsumori, Michihide" sort="Mitsumori, Michihide" uniqKey="Mitsumori M" first="Michihide" last="Mitsumori">Michihide Mitsumori</name>
</author>
<author><name sortKey="Robertson, John F R" sort="Robertson, John F R" uniqKey="Robertson J" first="John F R" last="Robertson">John F R. Robertson</name>
</author>
<author><name sortKey="Sasano, Hironobu" sort="Sasano, Hironobu" uniqKey="Sasano H" first="Hironobu" last="Sasano">Hironobu Sasano</name>
</author>
<author><name sortKey="Von Minckwitz, Gunter" sort="Von Minckwitz, Gunter" uniqKey="Von Minckwitz G" first="Gunter" last="Von Minckwitz">Gunter Von Minckwitz</name>
</author>
<author><name sortKey="Yamauchi, Akira" sort="Yamauchi, Akira" uniqKey="Yamauchi A" first="Akira" last="Yamauchi">Akira Yamauchi</name>
</author>
<author><name sortKey="Klimberg, V Suzanne" sort="Klimberg, V Suzanne" uniqKey="Klimberg V" first="V Suzanne" last="Klimberg">V Suzanne Klimberg</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2011">2011</date>
<idno type="RBID">pubmed:21431404</idno>
<idno type="pmid">21431404</idno>
<idno type="doi">10.1245/s10434-011-1666-7</idno>
<idno type="wicri:Area/PubMed/Corpus">002697</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002697</idno>
<idno type="wicri:Area/PubMed/Curation">002697</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002697</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002697</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002697</idno>
<idno type="wicri:Area/Ncbi/Merge">004223</idno>
<idno type="wicri:Area/Ncbi/Curation">004223</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004223</idno>
<idno type="wicri:Area/Main/Merge">004E70</idno>
<idno type="wicri:Area/Main/Curation">004E34</idno>
<idno type="wicri:Area/Main/Exploration">004E34</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Identifying gaps in the locoregional management of early breast cancer: highlights from the Kyoto Consensus Conference.</title>
<author><name sortKey="Toi, Masakazu" sort="Toi, Masakazu" uniqKey="Toi M" first="Masakazu" last="Toi">Masakazu Toi</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto, Japan. toi@kuhp.kyoto-u.ac.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawara-cho, Sakyo-ku, Kyoto</wicri:regionArea>
<orgName type="university">Université de Kyoto</orgName>
<placeName><settlement type="city">Kyoto</settlement>
<region type="prefecture">Région du Kansai</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Winer, Eric P" sort="Winer, Eric P" uniqKey="Winer E" first="Eric P" last="Winer">Eric P. Winer</name>
</author>
<author><name sortKey="Inamoto, Takashi" sort="Inamoto, Takashi" uniqKey="Inamoto T" first="Takashi" last="Inamoto">Takashi Inamoto</name>
</author>
<author><name sortKey="Benson, John R" sort="Benson, John R" uniqKey="Benson J" first="John R" last="Benson">John R. Benson</name>
</author>
<author><name sortKey="Forbes, John F" sort="Forbes, John F" uniqKey="Forbes J" first="John F" last="Forbes">John F. Forbes</name>
</author>
<author><name sortKey="Mitsumori, Michihide" sort="Mitsumori, Michihide" uniqKey="Mitsumori M" first="Michihide" last="Mitsumori">Michihide Mitsumori</name>
</author>
<author><name sortKey="Robertson, John F R" sort="Robertson, John F R" uniqKey="Robertson J" first="John F R" last="Robertson">John F R. Robertson</name>
</author>
<author><name sortKey="Sasano, Hironobu" sort="Sasano, Hironobu" uniqKey="Sasano H" first="Hironobu" last="Sasano">Hironobu Sasano</name>
</author>
<author><name sortKey="Von Minckwitz, Gunter" sort="Von Minckwitz, Gunter" uniqKey="Von Minckwitz G" first="Gunter" last="Von Minckwitz">Gunter Von Minckwitz</name>
</author>
<author><name sortKey="Yamauchi, Akira" sort="Yamauchi, Akira" uniqKey="Yamauchi A" first="Akira" last="Yamauchi">Akira Yamauchi</name>
</author>
<author><name sortKey="Klimberg, V Suzanne" sort="Klimberg, V Suzanne" uniqKey="Klimberg V" first="V Suzanne" last="Klimberg">V Suzanne Klimberg</name>
</author>
</analytic>
<series><title level="j">Annals of surgical oncology</title>
<idno type="eISSN">1534-4681</idno>
<imprint><date when="2011" type="published">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Breast Neoplasms (diagnosis)</term>
<term>Breast Neoplasms (therapy)</term>
<term>Congresses as Topic</term>
<term>Female</term>
<term>Humans</term>
<term>Prognosis</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Congrès comme sujet</term>
<term>Femelle</term>
<term>Humains</term>
<term>Pronostic</term>
<term>Tumeurs du sein ()</term>
<term>Tumeurs du sein (diagnostic)</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Congresses as Topic</term>
<term>Female</term>
<term>Humans</term>
<term>Prognosis</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Congrès comme sujet</term>
<term>Femelle</term>
<term>Humains</term>
<term>Pronostic</term>
<term>Tumeurs du sein</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A consensus conference was held to investigate issues related to the local management of early breast cancer. Here, we highlight the major topics discussed at the conference and propose ideas for future studies. Regarding axillary management, we examined three major issues. First, we discussed whether the use of axillary reverse mapping could clarify the lymphatic system of breast and whether the ipsilateral arm might help avoid lymphedema. Second, the use of an indocyanine green fluorescent navigation system was discussed for intraoperative lymphatic mapping. These new issues should be examined further in practice. Finally, some agreement was reached on the importance of "four-node diagnosis" to aid in the diagnostic accuracy of sentinel nodes. Regarding breast treatment, there was general agreement that the clinical value of surgical margins in predicting local failure was dependent on the tumor's intrinsic biology and subtypes. For patients treated with preoperative chemotherapy, less extensive excision may be feasible in those who respond to systemic therapy in an acceptable manner. Most trials of preoperative chemotherapy lack outcome data on local recurrence. Therefore, there is a need for such data for overview analysis. We also agreed that radiation after mastectomy may be beneficial in node-positive cases where more than four nodes are involved. Throughout the discussions for both invasive and noninvasive disease, the investigation of nomograms was justified for major issues in the decision-making process, such as the presence or absence of microinvasion and the involvement of nonsentinel nodes in sentinel node-positive patients.</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
</country>
<region><li>Région du Kansai</li>
</region>
<settlement><li>Kyoto</li>
</settlement>
<orgName><li>Université de Kyoto</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Benson, John R" sort="Benson, John R" uniqKey="Benson J" first="John R" last="Benson">John R. Benson</name>
<name sortKey="Forbes, John F" sort="Forbes, John F" uniqKey="Forbes J" first="John F" last="Forbes">John F. Forbes</name>
<name sortKey="Inamoto, Takashi" sort="Inamoto, Takashi" uniqKey="Inamoto T" first="Takashi" last="Inamoto">Takashi Inamoto</name>
<name sortKey="Klimberg, V Suzanne" sort="Klimberg, V Suzanne" uniqKey="Klimberg V" first="V Suzanne" last="Klimberg">V Suzanne Klimberg</name>
<name sortKey="Mitsumori, Michihide" sort="Mitsumori, Michihide" uniqKey="Mitsumori M" first="Michihide" last="Mitsumori">Michihide Mitsumori</name>
<name sortKey="Robertson, John F R" sort="Robertson, John F R" uniqKey="Robertson J" first="John F R" last="Robertson">John F R. Robertson</name>
<name sortKey="Sasano, Hironobu" sort="Sasano, Hironobu" uniqKey="Sasano H" first="Hironobu" last="Sasano">Hironobu Sasano</name>
<name sortKey="Von Minckwitz, Gunter" sort="Von Minckwitz, Gunter" uniqKey="Von Minckwitz G" first="Gunter" last="Von Minckwitz">Gunter Von Minckwitz</name>
<name sortKey="Winer, Eric P" sort="Winer, Eric P" uniqKey="Winer E" first="Eric P" last="Winer">Eric P. Winer</name>
<name sortKey="Yamauchi, Akira" sort="Yamauchi, Akira" uniqKey="Yamauchi A" first="Akira" last="Yamauchi">Akira Yamauchi</name>
</noCountry>
<country name="Japon"><region name="Région du Kansai"><name sortKey="Toi, Masakazu" sort="Toi, Masakazu" uniqKey="Toi M" first="Masakazu" last="Toi">Masakazu Toi</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004E34 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004E34 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:21431404 |texte= Identifying gaps in the locoregional management of early breast cancer: highlights from the Kyoto Consensus Conference. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21431404" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |